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Products - Cosmosil HPLC Columns
Cosmosil HPLC columns are based on high purity spherical silica gels giving excellent separation and reproducibility. With the technology and expertise that developed "TANAKA PLOT" known as a column evaluation method, our highly experienced scientists develop unique stationary phases and the highest quality HPLC columns. Each and every Cosmosil HLPC column is tested prior to sale and supplied with Inspection Report.
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COSMOSIL C18-MS-II: Monomeric C18
COSMOSIL 5C18-MS-II is a monomeric type of C18 phase.
- COSMOSIL 5C18-MS-II Guard Column
- COSMOSIL 5C18-MS-II Packed Column
- COSMOSIL 2.5C18-MS-II Packed Column
- COSMOSIL Guard Cartridge Holder
COSMOSIL C18-AR-II: Polymeric C18
COSMOSIL 5C18-AR-II is a polymeric type of C18 phase.
COSMOSIL C18-PAQ: For aqueous conditions
COSMOSIL 5C18-PAQ is designed to offer superior retention of polar compounds and excellent reproducibility in highly aqueous mobile phases, even in 100% aqueous.
Other reversed phases
COSMOSIL Buckyperp: Preparative separation of Fullerenes
COSMOSIL Buckyprep is a pyrenylpropyl group bonded silica based column specifically designed for fullerene separation. The unparalleled separation capabilities have enabled COSMOSIL Buckyprep to become the world benchmark of HPLC column for fullerene separation. COSMOSIL Buckyprep retains fullerenes very strongly with a mobile phase of 100% toluene and exceeds the injection volume of a standard C18 column by a factor of 35. Therefore, preparative-scale separation can be obtained with a 250 mm x 4.6 mm I.D. analytical column.
COSMOSIL Buckyprep-M: For Metallofullerenes
COSMOSIL Buckyprep-M is a phenothiazinyl group bonded silica based column specifically designed for metallo-fullerene separation. Metallo-fullerenes are retained more strongly than other fullerenes on this column. COSMOSIL Buckyprep-M is also effective for the separation of higher fullerenes and fullerene derivatives.
COSMOSIL PBB: Preparative separation of Fullerenes and higher Fullerenes.
COSMOSIL PBB is a pentabromobenzyl group bonded silica based column useful for preparative-scale separation of fullerenes. It can be used with carbon disulfide or 1,2,4-trichlorobenzene, which has greater solubility for fullerenes than toluene. The loading capacity of COSMOSIL PBB for C60 and C70 can be three times greater than COSMOSIL Buckyprep
COSMOSIL PYE, COSMOSIL NPE
COSMOSIL PYE (pyrenylethyl group bonded) and COSMOSIL NPE (nitrophenylethyl group bonded) column show unique retention characteristics based on multiple separation modes such as hydrophobic, charge transfer and π-π interactions. These columns are recommended for the separation of structural isomers.
- COSMOSIL 5PYE Guard Column
- COSMOSIL 5PYE Packed Column
- COSMOSIL 5NPE Guard Column
- COSMOSIL 5NPE Packed Column
COSMOSIL Cholester: Hydrophobic interaction and planarity selectivity
COSMOSIL Cholester is a new silica based RP column which employs a cholestery bonded phase. Cholester provides enhanced selectivity over traditional C18 materials and greater performance in separating isomers or other closely related compounds. Cholester is ideal for method development and serves as an excellent alternative to traditional C18 columns.
- COSMOSIL Cholester Guard Column
- COSMOSIL Cholester Packed Column
- COSMOSIL 2.5 Cholester Packed Column
COSMOSIL Sugar-D: Novel stationary phase for saccharide separation
Conventionally Aminopropyl bounded stationary phases are used for liquid chromatographic analysis of mono- and oligosaccharides. General shortcomings of the conventional Aminopropyl bounded phases are tailing and adsorption of certain saccharides and general low durability (short active life) of these columns. These problems are addressed and solved by the novel COSMOSIL Sugar-D, resulting in better (sharper) separation and much improved durability. In addition COSMOSIL Sugar-D is useful in the separation of highly hydrophilic compounds which are not retained in conventional octadecyl (ODS) bounded stationary phases.
COSMOSIL Diol-II: Aqueous gel filtration chromatography
COSMOSIL SL-II: Normal phase chromatography
COSMOSIL C18-OPN: Reversed Phase Open Column Chromatography
Open column chromatography is an excellent and easy technique for large scale preparation and purification at low cost. Reversed phase C18 packing materials are used but restricted to about 30-50% water in the mobile phase. The COSMOSIL C18-OPN is a new "Water-Wet" C18 packing material developed for Reversed Phase Open Column Chromatography. The C18-OPN material can be used in 100% aqueous eluents.
COSMOSIL C18-PREP: Process scale purifications
COSMOSIL HILIC: Hydrophilic interaction
COSMOSIL HILIC is a new column for hydrophilic interaction chromatography with Triazole bonded silica packing material. The hydrophilic interaction chromatography is a variation of normal phase chromatography where a polar stationary phase is used with a mobile phase which contains a high concentration of organic solvent and a low concentration of aqueous eluent. The main retention mechanism is the partitioning of the polar analytes between the polar stationary and the non-polar mobile phase. As it is also called "aqueous normal phase", the elution order is similar to that of normal phase and the sample elution is in the order of increasing hydrophilicity. Without using ion-pair reagent COSMOSIL HILIC retains highly polar analytes that would not be retained in reversed phase chromatography. It also shows a weak anion-exchange mechanism with the positively charged stationary phase, thus acidic compound is strongly retained.
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