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SunShell 2-Ethylpyridine

SunShell SFC Columns

SunShell 2-Ethylpyridine column is manufactured specifically for SFC applications using innovative core shell particle technology that provides significantly increased column efficiency and chromatographic resolution without the high back pressure seen in sub 2-µm columns.

 SunShell
2-Ethylpyridine
Silica Gel Core Shell Silica
Stationary Phase 2-ethylpyridine
Particle Size 2.6 µm 5 µm
Pore Size 90Å 90Å
Surface Area 150 m2/g 90 m2/g

 

Features of SunShell

- 2.6 µm core shell particle with 0.5 µm porous silica layer
- Provides the same high efficiency and high speed as sub-2 µm
- Less than half the backpressure of sub-2 µm
- Up to 100 times higher loading capacity compared to other core shell materials
- Improved pH stability from 1.0 to 10 (C18)

Comparison of SunShell 2-EP and sub-2µm particle 2-EP

Using a mixture of 17 small drug-like compounds under similar SFC conditions, SunShell 2-Ethylpridine column outperformed sub-2µm particle 2-ethylpyridine phases for overall selectivity.

Figure 1:
Chromatogram of the separation for the 17-component mix using the Sun Shell 2-EP column. A methanol gradient of < 2 minutes was used on the Agilent 1260 Infinity SFC system. SFC conditions: flow rate: 4.0mL/min; outlet pressure 160 bar; column temperature 55°C. Gradient program: 5.0-7.5% in 0.20 min, then 7.5-20% in 1.3 min and held at 20% for 0.2 min.

Figure 2:
Chromatogram of the separation for the 17-component mix using the Acquity UPC2 Viridis 2-EP column. 16 of the 17 components were resolved. A methanol gradient of < 2 minutes was used on the Agilent 1260 Infinity SFC system. SFC conditions: flow rate 3.5 mL/min; outlet pressure 160 bar; and column temperature 70°C. Gradient program: 5.0-12.5% in 1.0 min, 12.5% for 0.25 min, then 12.5-20% in 0.75 min.

Samples:
1. Caffeine, 2. Etophylline, 3. Thymine, 4. Uracil, 5. Flurbiprofen, 6. Naproxen, 7. Ketoprofen,
8. Cortisone, 9. Warfarin, 10. Hydrocortisone, 11. Prednisolone, 12. Acetamidophenol,
13 Sulfamethazine, 14. Sulfamethoxazole, 15. Sulfadimethoxine, 16. Sulfaquinoxazline,
17. Sulfamethizole

Ordering Information

SunShell 2-Ethylpyridine
Product Cat.No. Size Quantity Price(US$)  
SunShell 2-Ethylpyridine CE6931 2.1 mm I.D. x 30 mm 1 pkg 570.00 Buy
SunShell 2-Ethylpyridine CE6941 2.1 mm I.D. x 50 mm 1 pkg 630.00 Buy
SunShell 2-Ethylpyridine CE6951 2.1 mm I.D. x 75 mm 1 pkg 670.00 Buy
SunShell 2-Ethylpyridine CE6961 2.1 mm I.D. x 100 mm 1 pkg 690.00 Buy
SunShell 2-Ethylpyridine CE6971 2.1 mm I.D. x 150 mm 1 pkg 740.00 Buy
SunShell 2-Ethylpyridine CE6331 3.0 mm I.D. x 30 mm 1 pkg 570.00 Buy
SunShell 2-Ethylpyridine CE6341 3.0 mm I.D. x 50 mm 1 pkg 630.00 Buy
SunShell 2-Ethylpyridine CE6351 3.0 mm I.D. x 75 mm 1 pkg 670.00 Buy
SunShell 2-Ethylpyridine CE6361 3.0 mm I.D. x 100 mm 1 pkg 690.00 Buy
SunShell 2-Ethylpyridine CE6371 3.0 mm I.D. x 150 mm 1 pkg 740.00 Buy
SunShell 2-Ethylpyridine CE6431 4.6 mm I.D. x 30 mm 1 pkg 570.00 Buy
SunShell 2-Ethylpyridine CE6441 4.6 mm I.D. x 50 mm 1 pkg 630.00 Buy
SunShell 2-Ethylpyridine CE6451 4.6 mm I.D. x 75 mm 1 pkg 670.00 Buy
SunShell 2-Ethylpyridine CE6461 4.6 mm I.D. x 100 mm 1 pkg 690.00 Buy
SunShell 2-Ethylpyridine CE6471 4.6 mm I.D. x 150 mm 1 pkg 740.00 Buy
SunShell 2-Ethylpyridine, 5um CE3371 3.0 mm I.D. x 150 mm 1 pkg 740.00 Buy
SunShell 2-Ethylpyridine, 5um CE3471 4.6 mm I.D. x 150 mm 1 pkg 740.00 Buy