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COSMOSIL Quinoline

COSMOSIL SFC COLUMN / Quinoline group

The structural similarities between polar lipids, such as cholesterol and related analogs, have posed chromatographic and spectrometric challenges to analysts interested in quantifying these potential biomarkers. COSMOSIL Quinoline has been developed to improve the separation of these structural isomers utilizing the π-π interactions and structural rigidity of the naphthylethyl phase and the hydrogen bonding of the pyridine phase.

 

COSMOSIL Quinoline 
Silicagel high purity porous spherical silica
Average particle size 2.5 and 5µm
Average pore size approx. 120Å
Specific surface area approx. 300m2/g

Application 1: Steroids

Phase: Quinoline
Column size: 4.6 mmI.D. x 150 mm
Mobile phase: Carbon Dioxide (A) : Methanol (B)
Gradient: 2% - 7% B in 4 minutes
Flow rate: 4.5 ml/min
Pressure: 160 bar
Temperature: 30°C
Detection: APCI(+)

Application 2: Caffeine Analogs

Phase: Quinoline
Column size: 4.6 mmI.D. x 150 mm
Mobile phase: Carbon Dioxide : Methanol (95:5)
Flow rate: 4.5 ml/min
Pressure: 160 bar
Temperature: 30°C
Detection: UV260nm

Ordering Information

Particle Size: 2.5µm
Product Cat.No. Quantity Price(US$)  
COSMOSIL Quinoline Packed Column, 2.5µm, 3.0 mm I.D. x 50 mm NU05001 1 pkg 790.00 Buy
COSMOSIL Quinoline Packed Column, 2.5µm, 3.0 mm I.D. x 100 mm NU05003 1 pkg 790.00 Buy
COSMOSIL Quinoline Packed Column, 2.5µm, 3.0 mm I.D. x 150 mm NU05004 1 pkg 790.00 Buy
Particle Size: 5µm
Product Cat.No. Quantity Price(US$)  
COSMOSIL Quinoline Packed Column, 5µm, 2.0 mm I.D. x 150 mm NU00290 1 pkg 680.00 Buy
COSMOSIL Quinoline Packed Column, 5µm, 4.6 mm I.D. x 100 mm NU00300 1 pkg 650.00 Buy
COSMOSIL Quinoline Packed Column, 5µm, 4.6 mm I.D. x 150 mm NU00301 1 pkg 680.00 Buy
COSMOSIL Quinoline Packed Column, 5µm, 10.0 mm I.D. x 150 mm NU00302 1 pkg N/A Inquire
COSMOSIL Quinoline Packed Column, 5µm, 20.0 mm I.D. x 150 mm NU00303 1 pkg N/A Inquire
COSMOSIL Quinoline Packed Column, 5µm, 10.0 mm I.D. x 20 mm Inquiry 1 pkg N/A Inquire