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COSMOSIL PBr

COSMOSIL PBr / Pentabromobenzyl group

Supercritical Fluid Chromatography (SFC) has become more attractive because it offers some advantages over HPLC, such as high speed, unique selectivity and environmentally friendly separations. Many conventional normal-phase stationary phases, such as diol, amino and cyano, have been used for SFC applications. However, these phases present limitations for separations. COSMOSIL SFC Columns have been developed to enhance the capability of SFC separations.

 

COSMOSIL PBr 
Silicagel high purity porous spherical silica
Average particle size 5µm
Average pore size approx. 120Å
Specific surface area approx. 300m2/g

Comparison of Retention Behavior

The following three stationary phases were evaluated for their retention of hydrophilic, hydrophobic, acidic and basic compounds. COSMOSIL HP and PY elute hydrophobic compounds first and retain hydrophilic compounds longer, whereas PBr elutes in the reverse order, exhibiting high retention for hydrophobic compounds. HP had the longest retention for basic compounds.

Column size: 4.6 mmI.D. x 150 mm
Mobile phase:   A: CO2
B: 0.1% CH3COONH4 - Methanol
B conc. 0→50% (0→14min), 50% (14-17min)
Flow rate: 0.8 ml/min
BPR 10 MPa
Temperature: 40°C
Detection: ESI-MS/MS, MRM
Sample 

(No.1)  Uridine
(No.2)  3’ ,5’ -Dibenzyloxyacetophenone
(No.3)  4-Ethylbenzenesulfonic Acid
(No.4)  Benzyltrimethylammonium

Sample conc. 8 µmol/l
Inj. Vol 2.0 µl

 

Ordering Information

Analytical
Product Cat.No. End-Fitting Quantity Price(US$)  
COSMOSIL PBr Packed Column, 2.0 mm I.D. x 50 mm 12943-61 Waters type 1 pkg 450.00 Buy
COSMOSIL PBr Packed Column, 2.0 mm I.D. x 150 mm 12392-81 Waters type 1 pkg 600.00 Buy
COSMOSIL PBr Packed Column, 3.0 mm I.D. x 50 mm 12592-61 Waters type 1 pkg 350.00 Buy
COSMOSIL PBr Packed Column, 4.6 mm I.D. x 100 mm 12594-41 Waters type 1 pkg 480.00 Buy
COSMOSIL PBr Packed Column, 4.6 mm I.D. x 150 mm 12394-61 Waters type 1 pkg 500.00 Buy
COSMOSIL PBr Packed Column, 4.6 mm I.D. x 250 mm 12395-51 Waters type 1 pkg 630.00 Buy
Guard Cartridge/Column
Product Cat.No. End-Fitting Quantity Price(US$)  
COSMOSIL PBr Guard Cartridge, 4.6 mm I.D. x 10 mm 12444-14 Waters type 2 pkg 220.00 Buy
COSMOSIL Guard Cartridge Holder, 4.6 mm I.D. 38009-79 Waters type 1 pkg 250.00 Buy
COSMOSIL PBr Guard Column, 10.0 mm I.D. x 20 mm 12396-41 Waters type 1 pkg 530.00 Buy
Preparative
Product Cat.No. End-Fitting Quantity Price(US$)  
COSMOSIL PBr Packed Column, 10.0 mm I.D. x 250 mm 12397-31 Waters type 1 pkg 1,500.00 Buy
COSMOSIL PBr Packed Column, 20.0 mm I.D. x 250 mm 12398-21 Waters type 1 pkg 3,500.00 Buy