Nacalai USA - Innovations for Life Sciences

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Saccharide Separation

Conventionally Aminopropyl bounded stationary phases are used for liquid chromatographic analysis of mono- and oligosaccharides. General shortcomings of the conventional Aminopropyl bounded phases are tailing and adsorption of certain saccharides and general low durability (short active life) of these columns. These problems are addressed and solved by the novel COSMOSIL Sugar-D, resulting in better (sharper) separation and much improved durability. In addition COSMOSIL Sugar-D is useful in the separation of highly hydrophilic compounds which are not retained in conventional octadecyl (ODS) bounded stationary phases.

Certain types of saccharides such as Arabinose or Galactose are partially or temporarily absorbed in conventional Aminopropyl stationary phases causing disappearance of sample or tailing. These problematic saccharides elute sharply and in proportion of the injection volume from the superior COSMOSIL Sugar-D.

  • Different selectivity from aminopropyl columns
  • Superior quantitative results
  • Superior durability
  • Anomers remain unseparated
USP code N/A
Silica gel High purity porous spherical silica
Average particle size 5 µm
Stationary phase Secondary / tertiary amine


>> Information on COSMOSIL Sugar-D