Thiazovivin
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Cat. No.
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: NU03037 |
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Synonyms
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: N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide |
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CAS No.
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: 1226056-71-8 |
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Formula
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: C15H13N5OS (311.4) |
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Appearance
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: Off-white powder |
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Purity
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: 98% or more (HPLC), NMR (Conforms) |
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Solubilization
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: May be dissolved in DMSO (30 mg/ml)
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Storage
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: Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months. |
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Pharmacology
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: A ROCK inhibitor1. Dramatically improves (200-fold) the efficiency of induced pluripotent stem cell generation from human fibroblasts2. Induces direct conversion of porcine embryonic fibroblasts into adipocytes3. Improves survival of single hESCs on matrigel-coated plates after enzymatic dissociation (more than 30-fold)4. Cell permeable. |
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References
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: 1. E Kajabadi et al. Res. Pharm. Sci. 2012 7:S685 2. T Lin et al. Nature Methods 2009 6:805 3. J Zhu et al. Cell Reprogram. 2012 14:99 4. Y Xu et al. Proc. Natl. Acad. Sci. USA 2010 107:8129 |
Ordering Information
Small Molecules for Stem Cell Research
| Product | CAS No. | Purity | Storage | Cat.No. | PKG Size | Price | |
|---|---|---|---|---|---|---|---|
| Thiazovivin | 1226056-71-8 | 98% (HPLC) | -20°C | NU03037 | 5 mg | 118.00 | Buy |