Substrates
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N-Acetyl-D-mannosamine, Monohydrate [ManNAc]
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Origin
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: Prepared by enzymatic hydrolysis of N-Acetylneuraminic Acid, and purified by crystallization.
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Formula
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: C8H15NO6 • H2O (MW : 239.2)
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Appearance
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: White amorphous powder
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Purity
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: More than 99% by HPLC. Homogeneous by thin layer chromatographic analysis.
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Storage
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: Stable when stored on desiccated condition at 5oC.
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References
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: 1) K. Hotta, M. Kurokawa and S. Isaka, Seikagaku (in Japanese), 45 (10), 911-915 (1973)
2) S. Blayer, J. M. Woodley, M. J. Dawson and M. D. Lilly, Biotechnology and Bioengineering, 66 (2), 131-136 (1999)
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N-Glycolylneuraminic Acid [NeuGc; Neu5Gc; NeuNGc]
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Origin
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: Prepared by chemo-enzymatic synthesis from glucosamine and pyruvic acid.
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Formula
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: C11H19NO10 (MW : 325.27 )
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Appearance
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: White crystalline powder
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Purity
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: More than 98% by HPLC
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Storage
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: Stable when stored on desiccated condition below -20C.
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2,3-Dehydro-2-deoxy-N-acetylneuraminic Acid [NeuAc2en; NeuNAc2en; Neu5Ac2en]
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Origin
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: Prepared by chemical synthesis from N-acetylneuraminic acid.
Purified by column chromatography and crystallization.
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Formula
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: C11H17NO8 (MW : 291.25 )
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Appearance
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: White crystalline powder
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Purity
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: More than 95% by HPLC
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Use
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: Neuraminidase (sialidase) inhibitor
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Storage
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: Stable when stored on desiccated condition at -20C.
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N-Acetylneuraminic Acid [NANA; Sialic Acid; NeuAc]
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Origin
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: Prepared by enzymatic hydrolysis of Colominic Acid1), or enzymatic synthesis from N-Acetylglucosamine and Pyruvic Acid.2)
Purified by ion-exchange column chromatography and crystallization.
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Formula
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: C11H19NO9 (MW : 309.27)
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Appearance
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: White crystalline powder
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Purity
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: More than 99% by colorimetric determination and HPLC
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Use
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: Authentic specimen of the highest purity, substrate for NANA Aldolase and starting material for preparing NANA derivatives.
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Storage
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: Stable for one year when stored on desiccated condition at 5oC.
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References
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: 1) Y. Uchida, Y. Tsukada and T. Sugimori, Biochim. Biophys. Acta., 350, 425 (1974)
2) I. Maru, J. Ohnishi, Y. Ohta, and Y. Tsukada, Carbohydr. Res., 306, 575 (1998)
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N-Acetylneuraminic Acid Oligomers Sodium Salt [DP2-DP6]
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Origin
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: Prepared by hydrolysis of Colominic Acid.
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Formula
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: dimer (DP2) ... C22H34N2O17Na2 (MW : 644.50)
trimer (DP3) ... C33H50N3O25Na3 (MW : 957.73) tetramer (DP4) ... C44H66N4O33Na4 (MW : 1270.97) pentamer (DP5) ... C55H82N5O41Na5 (MW : 1584.21) hexamer (DP6) ... C66H98N6O49Na6 (MW : 1897.45) |
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Appearance
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: White amorphous powder , lyophilized
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Purity
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: More than 95% by HPLC
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Storage
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: Store below -20°C
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| Pakaging Size | : DP2 ... 10 mg , 100 mg, DP3 - DP6 : each 5 mg , 25 mg |
Cytidine-5'-monophospho-N-acetylneuraminic Acid, Disodium Salt [CMP-Neu5Ac・2Na]
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Origin
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: Prepared by enzymatic synthesis from N-Acetylneuraminic Acid and CTP.
Purified by ion-exchange column chromatography and lyophilization.
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Formula
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: C20H29N4O16PNa2 (MW : 658)
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Appearance
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: White lyophilized powder
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Purity
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: More than 97% by HPLC
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Storage
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: Stable when stored on desiccated condition below -20oC.
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Uridine-5'-diphosphoglucuronic Acid, Trisodium Salt
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Formula
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: C15H19N2O18P2Na3 (MW : 646.3)
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Appearance
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: White crystalline powder
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Purity
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: More than 98% (Moisture : approx. 12%)
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Storage
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: Stable when stored on desiccated condition at 5oC.
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Ordering Information
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