Taurine is a biologically significant molecule with a zwitterionic character, which makes it a difficult analysis target. COSMOSIL HILIC has a unique anion-exchange mechanism which allows strong retention of taurine with good peak shape. It is USP packing type L104, specified on the official monogram for taurine.

>> General information on COSMOSIL HILIC
https://www.nacalaiusa.com/products/view/96/cosmosil-hilic

>> USP revision notice for taurine (PDF file)
https://www.uspnf.com/sites/default/files/usp_pdf/EN/USPNF/revisions/taurine-rb-notice-20190301.pdf