Nacalai USA - Innovations for Life Sciences

Subtotal: $0.00

View Cart

COSMOSIL 1.8C18-MS-II

Sub-2 micron porous silica for UHPLC / Stable lot-to=lot quality and superior separation

Our UHPLC columns include COSMOSIL 1.8C18-MS-II, made with fully porous silica, and COSMOCORE 2.6C18, made with core-shell silica. Users should choose the appropriate column based on their instrument and analysis requirements. This pamphlet lists some characteristics of each column.

 
Fully porous silica
(COSMOSIL 1.8C18-MS-II)
Core-shell silica
Pore size about 12 nm about 9 nm
Specific surface area
about 340 m2/g
about 150 m2/g
Max. pressure 80 MPa 60 MPa
Usable pH range 2-10 * 2-10 *
 

Because the fully porous silica has pores throughout its structure, it can interact with the sample over a very wide surface area. As the amount of octadecyl phase that can be bonded increases, hydrophobic samples can be retained longer, leading to improved separation.

With core-shell silica’s nonporous core, sample dispersion is reduced; compared to fully porous columns, high theoretical plate numbers can be achieved even with larger particles. These larger particles result in lower backpressure, enabling use on conventional HPLC instruments.

*Silica gel columns are generally recommended to be used within pH 2–7.5. Outside this range, column degradation may happen more quickly.

Ordering Information

Product Cat.No. Storage PKG Size Price(US$)  
COSMOSIL 1.8C18-MS-II Packed Column (2.1 mmI.D. x 30 mm) 22132-71 RT 1 pkg 750.00 Buy
COSMOSIL 1.8C18-MS-II Packed Column (2.1 mmI.D. x 50 mm) 22136-31 RT 1 pkg 750.00 Buy
COSMOSIL 1.8C18-MS-II Packed Column (2.1 mmI.D. x 75 mm) 22137-21 RT 1 pkg 750.00 Buy
COSMOSIL 1.8C18-MS-II Packed Column (2.1 mmI.D. x 100 mm) 22138-11 RT 1 pkg 750.00 Buy
COSMOSIL 1.8C18-MS-II Packed Column (2.1 mmI.D. x 150 mm) 22139-01 RT 1 pkg 750.00 Buy