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Antigen Retrieval Solution: HistoVT One

Antigen retrieval solution

HistoVT One is an antigen retrieval solution for immunohistochemistry and in situ hybridization. This product can unmask antigenic sites without damage to antigen from formalin-fixed, frozen or paraffinembedded tissue sections.



  • Enhancing antigen-antibody reaction
  • Usable with frozen or paraffin-embedded tissue section
  • High reproducibility

Application data 1

Formalin-fixed, paraffine-embedded tissue sections

Data courtesy of RIKEN Brain Science Institute, Brain Development Research Group

Application data 2

Frozen sections

Data courtesy of RIKEN Brain Science Institute, Brain Development Research Group



  1. Seita, Y., et al. "Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells". eLife (2023). <<NEW!
  2. Sakata, Y. et al. "Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells". Dev Cell (2022). <<NEW!
  3. Pearson, GL, et al. "Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues." bioRxiv (2022).
  4. Igarashi, Tsutomu, et al. "Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice." Scientific Reports 12.1 (2022): 1-12.
  5. Cheng, Keren, et al. "The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys." Science advances 8.16 (2022): eabn8485.
  6. Shunsuke, Sanada, et al. "Intestinal microbial metabolite stercobilin involvement in the chronic inflammation of ob/ob mice." Scientific Reports (Nature Publisher Group) 10.1 (2020).    [Sample]  liver, white adipose tissues and colonic mucosa
  7. Hattori, Yuki, et al. "Transient microglial absence assists postmigratory cortical neurons in proper differentiation." Nature communications 11.1 (2020): 1-18.    [Sample]  mouse brain
  8. Lwin, Ohn Mar, et al. "Topical administration of mangiferin promotes healing of the wound of streptozotocin-nicotinamide-induced type-2 diabetic male rats." Journal of Dermatological Treatment (2020): 1-10.    [Sample] diabetic male rats
  9. Xu, Wenhua, et al. "Early ethanol exposure inhibits the differentiation of hippocampal dentate gyrus granule cells in a mouse model of Fetal Alcohol Spectrum Disorders." Alcoholism: Clinical and Experimental Research (2020).     [Sample]  mouse hippocampus
  10. Li, Hau-Wen, et al. "the characteristics and expression Profile of Transferrin in the Accessory Nidamental Gland of the Bigfin Reef Squid during Bacteria transmission." Scientific Reports 9.1 (2019): 1-11.    [Sample] squid
  11. Aziz, Nadine M., et al. "Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of Down syndrome." Journal of Neurodevelopmental Disorders 11.1 (2019): 1-17.    [Sample] mouse embryo, down syndrome
  12. Kalakuntla, Tej, and Johanes A. Santoso. "An Analysis of Differentiation and Integration of Retinoid Transplantations in RCS Rats."    [Sample]  rat retinal
  13. Lun, Melody P., et al. "Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome." The American journal of pathology 189.12 (2019): 2440-2449.     [Sample] mouse cortical neuron, LIG4 syndrome
  14. Yasuda, Katsutaro, et al. "A nonhuman primate model of liver fibrosis towards cell therapy for liver cirrhosis." Biochemical and Biophysical Research Communications (2020).
  15. Toda, Kazuya, et al. "Heat-Killed Bifidobacterium breve B-3 Enhances Muscle Functions: Possible Involvement of Increases in Muscle Mass and Mitochondrial Biogenesis." Nutrients 12.1 (2020): 219.
  16. Ito, Hidenori, et al. "Biochemical and morphological characterization of SEPT1 in mouse brain." Medical Molecular Morphology (2020): 1-8.
  17. Moro, Hiroshi, et al. "Epigenetic priming sensitizes gastric cancer cells to irinotecan and cisplatin by restoring multiple pathways." Gastric cancer 23.1 (2020): 105-115.
  18. Maeda, Hitoshi, et al. "Repeated Administration of Kupffer Cells-Targeting Nanoantioxidant Ameliorates Liver Fibrosis in an Experimental Mouse Model." Biological and Pharmaceutical Bulletin 43.1 (2020): 93-101.
  19. Ohta, Ken-ichi, et al. "The effects of early life stress on the excitatory/inhibitory balance of the medial prefrontal cortex." Behavioural brain research 379 (2020): 112306.
  20. Sasaki‐Takahashi, Natsu, et al. "The polarity and properties of radial glia‐like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy." Hippocampus 30.3 (2020): 250-262.
  21. Nishida, Manabu, et al. "Increased Tissue Expression of Lectin-Like Oxidized LDL Receptor-1 (LOX-1) Is Associated with Disease Severity in Chronic Rhinosinusitis with Nasal Polyps." Diagnostics 10.4 (2020): 246.
  22. Fujimura, Rui, et al. "α1-acid glycoprotein attenuates adriamycin-induced nephropathy via CD163 expressing macrophages induction." Kidney360 (2020): 10-34067.
  23. Kobayashi, Terumasa, et al. "Effects of Coffee Intake on Oxidative Stress During Aging-related Alterations in Periodontal Tissue." in vivo 34.2 (2020): 615-622.
  24. Coolen, Marion, et al. "Mosaic heterochrony in neural progenitors sustains accelerated brain growth and neurogenesis in the juvenile killifish N. furzeri." Current Biology 30.4 (2020): 736-745.
  25. Otake, Keita, et al. "Recovery of sensory function after the implantation of oriented-collagen tube into the resected rat sciatic nerve." Regenerative Therapy 14 (2020): 48-58.

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Ordering Information

Product Storage Cat.No. PKG Size Price  
HistoVT One (10x, pH 7.0) Room Temp. 06380-76 100 ml 76.00 Buy
HistoVT One (10x, pH 7.0) Room Temp. 06380-05 500 ml 229.00 Buy
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