Packing Materials for Column Chromatography
Open column chromatography is an excellent and easy technique for large-scale preparation and purification at low cost. COSMOSIL offers both normal and reversed phase packing materials based on totally porous spherical silica, which provides higher separation, less pressure and higher reproducibility than irregular silica.
Material Characteristics
| Packing Material | C18-OPN | C18-PREP | SL-II-PREP | Silica Gel 60 (neutral) |
| Silica Gel | High Purity Porous Spherical Silica | |||
| Average Particle Size | 75, 140 µm | 40, 75, 140 µm | 75, 140 µm | |
| Average Pore Size | approx. 120 Å | approx. 60 Å | ||
| Specific Surface Area | approx. 300 m2 /g | approx. 500 m2 /g | ||
| Stationary phase | Octadecyl Group | None | ||
| Carbon content | approx. 19% | 0% | ||
| End-capping treatment | None | Treated | - | - |
| Useful range | Open column chromatography / Flash column chromatography | |||
| Reversed phase chromatography | Normal phase chromatography | |||
Selection Guide
Reversed Phase
Normal Phase
