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Recombinant Human BCL2

B-cell lymphoma 2

BCL2 is a member of B cell lymphoma 2 (BCL2) family, which are key regulators in intrinsic apoptosis. BCL2 consists of a hydrophobic pocket to which BH3 helixes bind, preventing apoptosis and cell death. Overexpression of BCL2 has been reported in many cancers and the inhibition of BCL2 activity is a promising approach for cancer therapy.


Synonym(s):  B-cell lymphoma 2
Molecular Weight :  24.7 kDa
Tag :  C-terminal His Tag
Source : Escherichia Coli.
Purity :
Greater than 95%, as determined by SDS-PAGE 
Concentration : 0.6 mg/ml
Formulation :  25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 2 mM DTT, 10% Glycerol
GeneBank Accession # : P10415, a.a. 1-211
Application :  Inhibitor Screening, binding assays
Storage :  Stable for 12 months at -80°C, Avoid freeze/thaw cycles
Reference : 
Vogler, M., Adv Med. 2014. 2014:943648.
Hata, A., et al., Cancer Discov. 2015 May;5(5):475-87.

Ordering Information

Product Purity Storage Cat.No. PKG Size Price  
Recombinant Human BCL2 95 % or more (SDS-PAGE) -80°C NU03051 100 µg 426.00 Buy