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WELLBAG Cell Culture System - ACS1000SET

Automated Media Exchange / A Closed System for Contamination-Controlled Cell Culture

Is medium exchange in a CPC (Cell Processing Center) a burden?

The WELLBAG Cell Culture System enables efficient medium exchange directly within the bag while maintaining a closed system throughout the process. Up to three units can be operated simultaneously, helping streamline cell culture workflows.

Integrated sensors monitor the liquid level in each bag, enabling precise control of medium addition and removal.

 

Adopts a unique liquid thickness control method suitable for the bag culture

The pressure unit is equipped with a sensor to measure the thickness of the liquid in the bag, and while measuring the thickness of the liquid, it supplies new liquid and controls waste liquid. This method allows precise control of the liquid inside the bag despite its simple configuration.

Culture unit can be used in an incubator

A culture unit placed inside the incubator is connected via a cable to a control unit outs outside the incubator.

Microscopic Observation is possible while maintaining the closed system

The culture unit can be carried by removing the cable. Microscopic observation is possible through the glass surface of the pressure unit set on the culture unit.

Control by dedicated software

The culture system is controlled by dedicated software installed on the control computer. It is possible to set automatic culture medium exchange at any date and time.

Use a dedicated culture bag for the system

By using a WELLBAG dedicated to the system, it can be applied to complete medium exchange and differentiation induction during spheroid formation. In addition, the system-specific bag series, including a bag for adherent cells which currently under development, can be used.

Operation Overview Video

WELLBAG System Operation Video

 

WELLBAG-S500 Operation Overview Video

 

 

WELLBAG-L350 (large size) Operation Video

 

 

System Componets

WELLBAG Cell Culture System (ACS1000SET)

The system consists of the following components:

  • 1 x Control Unit (ACS1000) 
  • 3 x Culture Unit (CU1000) 
  • 3 x Holder Unit (HU1000)
  • 1 x Control PC (Software Installed) 

 

System Consumables

  • WELLBAG-S500-2PORTS (Culture Ares: 50 cm2, Culture Volume: 20 mL)
  • Medium Bag-S (Dual-Use for Supply / Waste) 
  • Pumping Tube-S (for peristaltic pump)

 

FAQ

Q1: How many consecutive days can media exchange be performed at most?
A1: We have confirmed that it can be performed for up to 40 days.
 
Q2: Can the culture unit be autoclaved sterilized?
A2: No. We recommend wiping it down with alcohol, hydrogen peroxide, or similar agents.
 
Q3: What is the media exchange rate in spheroid culture?
A3: Please refer to the evaluation example below. Media exchange performance in a well bag (for system use): Example By using 14.25 mL of medium for a 10 mL well bag, a 99% media exchange was achieved.  The migration rate of spheroids within the well bag during exchange was 0.5% or less.
What is the media exchange rate in spheroid culture?

Test conditions
Flow rate: 0.2 mL/min
Medium volume in the media bag: 10 mL

A media exchange rate of 99% or higher was confirmed after 40 minutes of pumping.

Ordering Information

Product Storage Cat.No. PKG Size Price  
WELLBAG Cell Culture System - ACS1000SET Room Temp. 71000-01 1 set - Inquire
System Consumables
Product Storage Cat.No. PKG Size Price  
WELLBAG-S500-2PORTS Room Temp. 11010-05 5 bags - Inquire
WELLBAG-S500-2PORTS Room Temp. 11010-10 10 bags - Inquire
WELLBAG-S500-2PORTS Room Temp. 11010-00 100 bags - Inquire
Medium Bag-S Room Temp. B1000-05 5 sets (10 bags) - Inquire
Medium Bag-S Room Temp. B1000-10 10 sets (20 bags) - Inquire
Medium Bag-S Room Temp. B1000-00 100 sets (200 bags) - Inquire
Pumping Tube-S Room Temp. T1000-05 5 sets (10 tubes) - Inquire
Pumping Tube-S Room Temp. T1000-10 10 sets (20 tubes) - Inquire
Pumping Tube-S Room Temp. T1000-00 100 sets (200 tubes) - Inquire

The shipping method is FedEx Ground or equivalent service.