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IBMX

Cat. No.
: NU03039
Synonyms
: 3-Isobutyl-1-methylxanthine
  3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
CAS No.
: 28822-58-4
Formula
: C10H14N4O2 (222.3)
Appearance
: White powder
Purity
: 99% or more (TLC), NMR (Conforms) 
Solubilization
: May be dissolved in DMSO (15 mg/ml); or ethanol (10 mg/ml)
Storage
: Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20°C for up to 3 months.
Pharmacology
:  Pan-specific inhibitor of phosphodiesterases (IC50=2-50 µM)1. Inhibition of PDEs leads to increased concentration of intracellular cAMP which activates PKA2. Does not inhibit PDE8 or PDE93. Weak adenosine receptor antagonist4.
References
: 1. JA Beavo et al. Mol. Pharmacol. 1970 6:597
  2. C Tomes et al. Cell. Signal. 1993 5:615
  3. SH Soderling et al. Curr. Opin. Cell Biol. 2000 12:174
  4. JW Daly et al. Prog. Clin. Biol. Res. 1987 230:41

Ordering Information

Small Molecules for Stem Cell Research
Product CAS No. Purity Storage Cat.No. PKG Size Price  
IBMX 28822-58-4 98% (TLC) Room Temp. NU03039 100 mg 38.00
Buy
IBMX 28822-58-4 98% (TLC) Room Temp. NU03039-2 250 mg 80.00
Buy