Core-shell particles consist of a nonporous core inside a porous shell. By using these core-shell particles, one can achieve sharper peaks compared to fully porous silica gel particles of the same diameter.
Compared to fully porous particles, core-shell particles have a more uniform particle diameter therefore, core-shell particles can be packed in the column more uniformly to minimize sample diffusion.
COSMOCORE 2.6C18 (200x) Fully porous 1.7 µm particles (200x)
Mass transfer refers to the time it takes for a sample molecule to enter and leave a particle. In general, lower mass transfer time corresponds to less diffusion and sharper peaks. Even though COSMOCORE 2.6C18 has a larger particle diameter than fully porous sub-2 µm particles, the mass transfer characteristics are similar.
COSMOCORE 2.6C18 Fully porous sub-2 µm particle
|Column||COSMOCORE 2.6C18||COSMOCORE 2.6Cholester||COSMOCORE 2.6PBr|
|USP Code||L 101|
|Silica Gel||Core-shell type silica|
|Particle Size||2.6 µm|
|Average Pore Size||1.6 µm|
|Pore Size||approx. 90 Å|
|Specific Surface Area||approx. 150 m2/g|
|Main Interaction||Hydrophobic interaction||
Molecular shape selectivity
|End Capping||Near-perfect Treatment|
|Carbon Content||approx. 7 %||-||-|
|pH Range||1.5 - 10||2.0 - 7.5||2.0 - 7.5|
|Max. Puressure||60 MPa|