Recombinant Human Kras Wild-Type and mutants
| Kras is a member of the RAS protein family, which are a class of small GTPases involved in cell signaling. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. |
|
Synonym(s):
|
KRAS2, RASK2
|
|
Molecular Weight :
|
49.6 kDa
|
|
Tag :
|
N-GST tagged
|
|
Source :
|
E. coli
|
|
Purity :
|
Greater than 95%, as determined by SDS-PAGE
 |
|
Concentration :
|
0.5 mg/ml
|
|
Formulation :
|
PBS + 20% glycerol
|
|
GeneBank Accession # :
|
P01116, a.a. 1-169
|
|
Application :
|
Inhibitor Screening, Binding Assays
|
|
Storage :
|
Stable for 12 months at -80°C, Avoid freeze/thaw cycles
|
|
Reference :
|
Tam, I.Y., et al. Clin Cancer Res. 2006;12(5):1647-1653.
Fernández-Medarde A., et al. Genes (Basel). 2021;12(5):681.
|
Ordering Information
| Product | Cat.No. | Purity | Storage | PKG Size | Price(US$) | |
|---|---|---|---|---|---|---|
| Recombinant Human Kras Wild-Type (WT), GST-Tag | NU03043-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras Wild-Type (WT), GST-Tag | NU03043-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras Wild-Type (WT), GST-Tag, GDP Loaded | NU03043-1G | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras Wild-Type (WT), GST-Tag, GDP Loaded | NU03043-2G | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras Wild-Type (WT), GST-Tag, GppNHp Loaded | NU03043-1GP | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras Wild-Type (WT), GST-Tag, GppNHp Loaded | NU03043-2GP | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag | NU03044-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag | NU03044-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag, GDP Loaded | NU03044-1G | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag, GDP Loaded | NU03044-2G | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag, GppNHp Loaded | NU03044-1GP | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12C), GST-Tag, GppNHp Loaded | NU03044-2GP | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12C), His-Tag | NU03019-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras (G12C), His-Tag | NU03019-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag | NU03045-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag | NU03045-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag, GDP Loaded | NU03045-1G | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag, GDP Loaded | NU03045-2G | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag, GppNHp Loaded | NU03045-1GP | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12D), GST-Tag, GppNHp Loaded | NU03045-2GP | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag | NU03046-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag | NU03046-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag, GDP Loaded | NU03046-1G | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag, GDP Loaded | NU03046-2G | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag, GppNHp Loaded | NU03046-1GP | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12R), GST-Tag, GppNHp Loaded | NU03046-2GP | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag | NU03047-1 | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 299.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag | NU03047-2 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 499.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag, GDP Loaded | NU03047-1G | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag, GDP Loaded | NU03047-2G | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag, GppNHp Loaded | NU03047-1GP | 95 % or more (SDS-PAGE) | -80°C | 50 µg | 339.00 | Buy |
| Recombinant Human Kras (G12V), GST-Tag, GppNHp Loaded | NU03047-2GP | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 569.00 | Buy |
| Recombinant Human RBD-Raf-1, His-Tag | NU03056-1 | 95 % or more (SDS-PAGE) | -80°C | 100 µg | 439.00 | Buy |