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Recombinant Human Kras Wild-Type and mutants

Kras is a member of the RAS protein family, which are a class of small GTPases involved in cell signaling. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. 

 

Synonym(s): 
KRAS2, RASK2
Molecular Weight : 
49.6 kDa
Tag : 
N-GST tagged
Source :
E. coli
Purity :
Greater than 95%, as determined by SDS-PAGE
Concentration :
0.5 mg/ml
Formulation : 
PBS + 20% glycerol
GeneBank Accession # :
P01116, a.a. 1-169
Application : 
Inhibitor Screening, Binding Assays
Storage : 
Stable for 12 months at -80°C, Avoid freeze/thaw cycles
Reference : 
Tam, I.Y., et al. Clin Cancer Res. 2006;12(5):1647-1653.
Fernández-Medarde A., et al. Genes (Basel). 2021;12(5):681.

Ordering Information

Product Cat.No. Purity Storage PKG Size Price(US$)  
Recombinant Human Kras Wild-Type (WT), GST-Tag NU03043-1 95 % or more (SDS-PAGE) -80°C 50 µg 149.00 Buy
Recombinant Human Kras Wild-Type (WT), GST-Tag NU03043-2 95 % or more (SDS-PAGE) -80°C 100 µg 299.00 Buy
Recombinant Human Kras (G12C), Gst-Tag NU03044-1 95 % or more (SDS-PAGE) -80°C 50 µg 149.00 Buy
Recombinant Human Kras (G12C), Gst-Tag NU03044-2 95 % or more (SDS-PAGE) -80°C 100 µg 299.00 Buy
Recombinant Human Kras (G12D), Gst-Tag NU03045-1 95 % or more (SDS-PAGE) -80°C 50 µg 149.00 Buy
Recombinant Human Kras (G12D), Gst-Tag NU03045-2 95 % or more (SDS-PAGE) -80°C 100 µg 299.00 Buy
Recombinant Human Kras (G12R), Gst-Tag NU03046-1 95 % or more (SDS-PAGE) -80°C 50 µg 149.00 Buy
Recombinant Human Kras (G12R), Gst-Tag NU03046-2 95 % or more (SDS-PAGE) -80°C 100 µg 299.00 Buy
Recombinant Human Kras (G12V), Gst-Tag NU03047-1 95 % or more (SDS-PAGE) -80°C 50 µg 149.00 Buy
Recombinant Human Kras (G12V), Gst-Tag NU03047-2 95 % or more (SDS-PAGE) -80°C 100 µg 299.00 Buy