
For mass cell culture / Polyvinyl Alcohol (PVA) microcarriers - Scapova™

Microcarriers are micron-sized beads used as scaffolds for cell culture. Cells attach to the bead surface and proliferat on it.

The microcarriers have higher cell proliferation capability than competitors

It can be applied to the culture of therapeutic cells such as MSCs.
Strict quality management and no risk of contamination due to the material features

SCAPOVA™ CL is “Ready to use.” No need for sterilization and cleaning before use. It swells quickly in PBS or culture medium. Swollen particles are highly transparent. Therefore, cells can be easily observed with a phase contrast microscope.

| SCAPOVA CL | SCAPOVA AS | |
|
Clinical grade collagen is coated on the particle surface. |
|
|
| Particle size (D50) | 220 μm | 160 μm |
| Surface | Collagen coated | Activated treatment |
| Swelling factor (in PBS) | 10 | 5 |
| The surface area [/g dry weight] | 2,600 cm2 | 1,900 cm2 |
| Sterilization | Gamma irradiation | Gamma irradiation |
*Scapova AS needs a coating of cell-adhesion molecules before use. Coating materials tested are Vitronectin, fibronectin, Laminin, iMatrix-511, Synthemax II, Poly-L-Lysine and Collagen. Please refer to the manual for the coating protocol.
Kida, Katsuhiko, Daisuke Hatanaka, Shiho Anno, Miki Nakajima, and Masaki Kobayashi. "FP003B suppresses microcarrier aggregation and enhances cell yield in microcarrier-based mesenchymal stromal cell culture." Frontiers in Bioengineering and Biotechnology 14: 1881013.
Pasanen, Shiina, Fumika Abe, Karina Erda Saninggar, Isao Hirata, Kotaro Tanimoto, and Koichi Kato. "Enhanced Expansion of Bone Marrow-Derived Mesenchymal Stem Cells on Collagen-Coated Microcarriers Functionalized with Chimeric IGF-1–bFGF Proteins." ACS omega 11, no. 18 (2026): 27266.
*** For Research Use Only (RUO) ***
These products are for research use only and may not be used for clinical, diagnostic, or therapeutic purposes.