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PVA Microcarriers - Scapova™

For mass cell culture / Polyvinyl Alcohol (PVA) microcarriers - Scapova™

Features
  • High cell proliferation rate
  • Quality management in accordance with medical standards
  • Ease of handling

About Microcarriers

Microcarriers are micron-sized beads used as scaffolds for cell culture. Cells attach to the bead surface and proliferat on it. 

High cell proliferation rate

The microcarriers have higher cell proliferation capability than competitors

It can be applied to the culture of therapeutic cells such as MSCs.

Quality management in accordance with medical standards

Strict quality management and no risk of contamination due to the material features

Ease of handling

SCAPOVA™ CL is “Ready to use.” No need for sterilization and cleaning before use. It swells quickly in PBS or culture medium. Swollen particles are highly transparent. Therefore, cells can be easily observed with a phase contrast microscope.

Scapova CL and Scapova AS

  SCAPOVA CL SCAPOVA AS
 

Clinical grade collagen is coated on the particle surface. 


The particle surface is specially treated and activated. 
By activation, any cell adhesion molecules can be coated.*

Particle size (D50) 220 μm 160 μm
Surface Collagen coated Activated treatment
Swelling factor (in PBS) 10 5
The surface area [/g dry weight] 2,600 cm2 1,900 cm2
Sterilization  Gamma irradiation Gamma irradiation

*Scapova AS needs a coating of cell-adhesion molecules before use.  Coating materials tested are Vitronectin, fibronectin, Laminin, iMatrix-511, Synthemax II, Poly-L-Lysine and Collagen.  Please refer to the manual for the coating protocol. 

Reference

Kida, Katsuhiko, Daisuke Hatanaka, Shiho Anno, Miki Nakajima, and Masaki Kobayashi. "FP003B suppresses microcarrier aggregation and enhances cell yield in microcarrier-based mesenchymal stromal cell culture." Frontiers in Bioengineering and Biotechnology 14: 1881013.

 

Pasanen, Shiina, Fumika Abe, Karina Erda Saninggar, Isao Hirata, Kotaro Tanimoto, and Koichi Kato. "Enhanced Expansion of Bone Marrow-Derived Mesenchymal Stem Cells on Collagen-Coated Microcarriers Functionalized with Chimeric IGF-1–bFGF Proteins." ACS omega 11, no. 18 (2026): 27266.

 

Kaneko, Masahiro, Airi Sato, Satoru Ayano, Akio Fujita, Goro Kobayashi, and Akira Ito. "Expansion of human mesenchymal stem cells on poly (vinyl alcohol) microcarriers." Journal of bioscience and bioengineering 136, no. 5 (2023): 407-414.

Ordering Information

PVA Microcarriers
Product Storage Cat.No. PKG Size Price  
SCAPOVA™ CL Room Temp. M11018SAC1-10GB 10 g 650.00
Buy
SCAPOVA™ AS Room Temp. M11018PF00-10GB 10 g 600.00
Buy

*** For Research Use Only (RUO) ***
These products are for research use only and may not be used for clinical, diagnostic, or therapeutic purposes.