Protein Separation Columns

Arg-SEC Mobile Phase

Effective separation of protein conjugates, e.g., ADC and sticky cytokines / Universal mobile phase for size-exclusion chromatography

Size-Exclusion Chromatography (SEC) is an essential technology for developing biopharmaceuticals. SEC is normally carried out in aqueous solution so that the mobile phase has a minimal impact on the target biopharmaceutical proteins, e.g., ...

Cat.No.: 16998-41, 16999-31, 17000-51

COSMOSIL Application Data

Application : Cannabinoids Analysis

Small Molecules Separation

mRNA and Oligonucleotides Purification

mRNA and Oligonucleotides purification with chromatography

RNA based therapeutics represent a powerful new tool for gene therapy. In RNA production, impurities such as nucleotide triphosphates, abortive transcripts, and DNA template can affect down-stream applications by triggering immune responses...

Cat.No.: 12614-71, 22524-41, 21078-31, 21079-21, 21080-81, 21088-01, 19380-21, 20785-91, 21095-01, 19381-11, +2 more

COSMOSIL Application Data

COSMOSIL Application Search: Over 8,000 Data

COSMOSIL Application, which includes more than 8,000 applications using COSMOSIL/COSMOCORE columns, is now usable by clicking the link below which is in Nacalai Tesque, Inc. The application is searchable by sample category, sample name, CAS...

COSMOSIL Selection Guide / Technical Note

Technical Notes

The below link will direct you to Nacalai Tesque site. >> FAQ and Troubleshooting >> Technical Information >> Performance Guarantee and Validation Kits >> Column Instruction Manuals >> Technical Guide f...

COSMOSIL Application Data

Application Notes / Posters

COSMOSIL Selection Guide / Technical Note

Column Selection Guide

• Organic Compounds (Low M.W.) Octadecyl group bonded column (C18, ODS) are recommended as first-choice columns for separations of organic compounds (Low M.W.). If there is not enough separation or no retention using COSMOSIL C18 co...

Core-Shell Based Columns (COSMOCORE)

About Core Shell Particles

Core-shell particles consist of a nonporous core inside a porous shell. By using these core-shell particles, one can achieve sharper peaks compared to fully porous silica gel particles of the same diameter. ...

Preparative Packing Materials for Column Chromatography

Packing Materials for Column Chromatography

Open column chromatography is an excellent and easy technique for large-scale preparation and purification at low cost. COSMOSIL offers both normal and reversed phase packing materials based on totally porous spherical silica, which provide...

Preparative Packing Materials for Column Chromatography

Silica Gel for Column Chromatography

Since conventional silica gels are weakly acidic, some pH sensitive compounds may be decomposed during the purification by column chromatography with the acidic silica gels. The pH of Silica Gel 60 (spherical neutral) is adjusted to nearly ...

Cat.No.: 30724-55, 30724-71, 30724-84, 30721-85, 30721-01, 30721-14, 30731-71, 30731-42, 30734-41, 30511-64, +7 more