Reversed Phase C18 Series

Instrument Settings for COSMOCORE Columns

Using COSMOCORE columns with a conventional (non-UHPLC) instrument

COSMOCORE columns are designed for use with UHPLC instruments. In addition, due to their low backpressure, they can be used with conventional instruments. However, it is necessary to change the following settings.

Cat.No.: 37843-69, 12570-41, P0402, 12571-31, 12572-21, 15767-91

HPLC Accessories

Labeling Reagent for LC-MS

L-FDVDA (1-Fluoro-2,4-dinitrophenyl-5-L-valine-N,N-dimethylethylenediamine-amide) This product is a red to red-yellow crystal or powder that dissolves in acetone. It is a labeling reagent for amino groups and includes a chiral carbon, ...

Cat.No.: 20363-24

Selection Guide / Technical Note / Application Data

HPLC Column Manuals

Manuals are available for COSMOSIL, COSMOCORE, and COSMOGEL series products. Type Packing material Manual (PDF) Reversed phase and normal phase columns, particle size 5 µm, 15 µm * Excluding guard cartridg...

Selection Guide / Technical Note / Application Data

Application : Comparison of biphenyl and other aromatic stationary phases

Many of our columns feature aromatic ring-based stationary phases with strong π-π interactions, notably our πNAP (naphthylethyl) and PYE (pyrenylethyl) columns. Several other companies produce similar columns using a biphenyl phase...

Reversed Phase C18 Series

Conventional Columns (Old Type COSMOSIL)

Cat.No.: 39047-81, 39265-21, 37861-61, 37862-51, 37971-21, 37972-11, 39103-31, 39280-11, 39150-11, 39290-81

Reversed Phase C18 Series

COSMOSIL 1.8C18-MS-II (Sub-2 micron porous silica for UHPLC)

Sub-2 micron porous silica for UHPLC / Stable lot-to=lot quality and superior separation

Our UHPLC columns include COSMOSIL 1.8C18-MS-II, made with fully porous silica, and COSMOCORE 2.6C18, made with core-shell silica. Users should choose the appropriate column based on their instrument and analysis requirements. This pamphlet...

Cat.No.: 22132-71, 22136-31, 22137-21, 22138-11, 22139-01, 22396-31, 22397-21

Reversed Phase C18 Series

COSMOSIL 3C18-SS

Perfecting Chemical Modification Technology

COSMOSIL 3C18-SS is the product of perfecting our chemical modification and endcapping technology, enabling this column to withstand alkaline and acidic mobile phases. It also resists peak tailing, and with the 3 μm particle size, fast a...

Cat.No.: 22560-61, 22542-01, 22543-91, 22546-61, 22547-51, 22548-41, 22549-31, 22550-91, 22551-81, 22552-71, +12 more

Reversed Phase Specialty Columns

COSMOSIL 1.8PBr (Sub-2 micron porous silica for UHPLC)

High‑speed separation with UHPLC (1.8 μm particles) / Pentabromobenzyl group stationary phase

Features Retain hydrophilic compounds with reversed‑phase chromatography Significantly improved separation compared to ODS columns High‑speed separation with UHPLC (1.8 μm particles)

Cat.No.: 22739-41, 22740-01, 22741-91, 22742-81, 22743-71, 22744-61, 22745-51, 22746-41

mRNA and Oligonucleotides Purification

HFIP for Nucleic Acid Analysis

For impurity analysis of oligonucleic acids using HPLC or LC-MS

1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) is frequently used as a mobile phase additive for analysis of oligonucleotides below 100 nucleotides (nt) and their impurities, due to the high sensitivity and separation it enables. However, there a...

Cat.No.: 22941-42

SunShell HPLC Columns

SunShell C18 / SunShell C8

SunShell HPLC Columns

SunShell HPLC columns are manufactured using innovative core shell particle technology that provides significantly increased column efficiency and chromatographic resolution without the high back pressure seen in sub-2 µm columns. Fe...

Cat.No.: CB6J4P, CB6J7P, CB6H4P, CB6H7P, CB6K4P, CB6K7P, CB6G4P, CB6G7P, CB6F48, CB6F78, +53 more