Selection Guide / Technical Note / Application Data

Technical Notes

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Selection Guide / Technical Note / Application Data

Application Notes / Posters

Selection Guide / Technical Note / Application Data

Column Selection Guide

• Organic Compounds (Low M.W.) Octadecyl group bonded column (C18, ODS) are recommended as first-choice columns for separations of organic compounds (Low M.W.). If there is not enough separation or no retention using COSMOSIL C18 co...

Reversed Phase C18 Series

About Core Shell Particles

Core-shell particles consist of a nonporous core inside a porous shell. By using these core-shell particles, one can achieve sharper peaks compared to fully porous silica gel particles of the same diameter. ...

Preparative Packing Materials for Column Chromatography

Packing Materials for Column Chromatography

Open column chromatography is an excellent and easy technique for large-scale preparation and purification at low cost. COSMOSIL offers both normal and reversed phase packing materials based on totally porous spherical silica, which provide...

Preparative Packing Materials for Column Chromatography

Silica Gel for Column Chromatography

Since conventional silica gels are weakly acidic, some pH sensitive compounds may be decomposed during the purification by column chromatography with the acidic silica gels. The pH of Silica Gel 60 (spherical neutral) is adjusted to nearly ...

Cat.No.: 30724-55, 30724-71, 30724-84, 30721-85, 30721-01, 30721-14, 30731-71, 30731-42, 30734-41, 30511-64, +7 more

HPLC Accessories

Ion Pair Reagents

The use of ion pair reagents as mobile phase additives extends the applicability of reversed phase HPLC. Ionic or highly polar compounds are difficult to analyze by reversed phase using only organic solvent and buffer solution because of th...

Cat.No.: 32824-72, 32935-64, 32935-22, 32924-62, 32905-54, 32905-12, 32929-54, 32926-26, 32926-84, 31730-64, +11 more

Selection Guide / Technical Note / Application Data

COSMOSIL Catalog / Technical Notes (PDF)

COSMOSIL HPLC Catalog 12 Edition COSMOSIL HPLC Catalog 2019 We have released revised technical notes for our COSMOSIL HPLC columns. These include information for our new core-shell and SFC products. Please consult them wh...

SFC (Supercritical Fluid Chromatography) Columns

COSMOSIL SFC Column Series

Supercritical Fluid Chromatography (SFC) has become more attractive because it offers some advantages over HPLC, such as high speed, unique selectivity and environmentally friendly separations. Many conventional normal-phase stationary phas...

Cat.No.: 21567-21, 18253-21, 18252-31, 18678-71, 18869-71, 13559-81, 13560-41, 13845-21, 15751-81, 13971-61, +26 more

Protein Separation Columns

Arg-Antibody Elution Buffer, pH4.0

This product leads to effective elution of antibodies from protein A columns under mild pH (pH 4.0). Normally, antibodies are not effectively eluted at pH 4.0. Use of a lower pH can lead to partial denaturation and subsequent aggregation of...